Hydrochloric Acid → [6-[(4-Chlorophenylsulfonyl)(2,5-difluorophenyl)methyl]pyridin-3-yl]methylamine hydrochloride

Participants

Reaction Steps

To an ethanol (2 ml) solution of t-butyl[[6-[(4-chlorophenylsulfonyl)(2,5-difluorophenyl)methyl]pyridin-3-yl]methyl]-N-(t-butoxycarbonyl)carbamate (70 mg, 0.115 mmol) was added concentrated hydrochloric acid (2 ml). The resulting mixture was stirred at room temperature for 3 hours. The reaction mixture was concentrated under reduced pressure. To the residue thus obtained was added ethanol. The resulting mixture was concentrated under reduced pressure to give the title compound (51 mg, 0.115 mmol, 100%) as a white powder.

Provenance & Evidence