4,5-Dihydroxy-1,3-dimethylimidazolidin-2-one → 1,3-Dimethylimidazolidine-2,4-dione

In a 200 ml glass vessel equipped with a stirrer, thermometer, a dropping funnel and a distillation unit were charged 60 g (0.41 mol) of 4,5-dihydroxy-1,3-dimethyl-2-imidazolidinone and 60 ml of water. And then, the mixture was reacted at 100° C. to 200° C. for 2 hours while removing water under normal pressure by distillation. The obtained residue was evaporated under reduced pressure (109 to 117° C./0.53 to 0.67 kPa) to obtain 41 g (Isolation yield; 78%) of 1,3-dimethylimidazolidin-2,4-dione as a pale yellow liquid.

1. customIn a 200 ml glass vessel equipped with a stirrer
2. customAnd then, the mixture was reacted at 100° C. to 200° C. for 2 hours
3. customwhile removing water under normal pressure
4. distillationby distillation
5. customThe obtained residue was evaporated under reduced pressure (109 to 117° C./0.53 to 0.67 kPa)

ORD record

ord-129fadaa91ac4bcfb5e4e3cc5a7365e0

Source dataset

uspto-grants-2011_04

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US07932400B2