反应详情

The compound (0.78 g) obtained in Example 1-5 was dissolved in methanol (20 ml) and added with 2-imidazole carboxaldehyde (214 mg) and the whole was stirred at room temperature for 17 hours. After the solvent was distilled off, the resultant was dried under vacuum, dissolved in methanol (15 ml), and then added with sodium borohydride (217.8 mg). The whole was stirred at room temperature for 45 minutes. The reaction solution was added with a saturated aqueous ammonium chloride solution (10 ml) and stirred at room temperature for 15 minutes.

1. distillationAfter the solvent was distilled off
2. customthe resultant was dried under vacuum
3. dissolutiondissolved in methanol (15 ml)
4. additionadded with sodium borohydride (217.8 mg)
5. stirringThe whole was stirred at room temperature for 45 minutes
6. additionThe reaction solution was added with a saturated aqueous ammonium chloride solution (10 ml)
7. stirringstirred at room temperature for 15 minutes