反应详情

The compound (173 mg) obtained in Example 3-5 was dissolved in a 40% methylamine/methanol solution (1.8 ml) and the whole was stirred at room temperature for 17 hours. After completion of the reaction, the solvent was distilled off under reduced pressure and the residue was then purified through silica gel column chromatography (chloroform/ethyl acetate), thereby obtaining the subject compound (130 mg) as a pale-yellow oily substance.

1. customAfter completion of the reaction
2. distillationthe solvent was distilled off under reduced pressure
3. customthe residue was then purified through silica gel column chromatography (chloroform/ethyl acetate)