Methanol → HCID 67103855, compound

Participants

Reaction Steps

The compound (265 mg) obtained in Example 63-1 was dissolved in anhydrous methanol (2.5 ml) and added with a 4 mol/l hydrogen chloride/dioxane solution (5.00 ml) and the whole was stirred overnight at room temperature. After completion of the reaction, the solvent was distilled off. The resultant was added with a saturated aqueous sodium hydrogen carbonate solution. The whole was subjected to extraction with chloroform and washed with a saturated saline solution. The organic layer was dried with anhydrous sodium sulfate. The solvent was distilled off, thereby obtaining the subject compound (161 mg) as a pale-yellow oily substance.

Provenance & Evidence