Ethanol → HCID 11584661, compound
Reaction equation
[NH:1]1[CH:5]=[CH:4][N:3]=[C:2]1[CH2:6][N:7]([CH2:14][C:15]1[CH:37]=[CH:36][C:18]([CH2:19][N:20]([CH2:32][C:33]([OH:35])=[O:34])[CH2:21][CH2:22][CH2:23][CH2:24][N:25]([CH2:29][CH2:30][CH3:31])[CH2:26][CH2:27][CH3:28])=[CH:17][CH:16]=1)[CH2:8][C:9]1[NH:10][CH:11]=[CH:12][N:13]=1.[CH2:38](O)[CH3:39]>>[CH2:38]([O:34][C:33](=[O:35])[CH2:32][N:20]([CH2:19][C:18]1[CH:36]=[CH:37][C:15]([CH2:14][N:7]([CH2:8][C:9]2[NH:13][CH:12]=[CH:11][N:10]=2)[CH2:6][C:2]2[NH:1][CH:5]=[CH:4][N:3]=2)=[CH:16][CH:17]=1)[CH2:21][CH2:22][CH2:23][CH2:24][N:25]([CH2:29][CH2:30][CH3:31])[CH2:26][CH2:27][CH3:28])[CH3:39]Participants
3
Procedure
The compound (275.6 mg) obtained in Example 69-1 was dissolved in ethanol (11 ml) and the whole was refluxed under heating for 21 hours.
Workup
- temperaturethe whole was refluxed
- temperatureunder heating for 21 hours
Sources & evidence
- ORD record
- ord-8bee5a5b09304a8caf8138421bf0b0af
- Source dataset
- uspto-grants-2011_04
- Patent number
- US07932281B2
Reaction notes
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