HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Dihydroxyboranyl)-5-nitrobenzoic acid → 3-Amino-5-carboxybenzeneboronic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Dihydroxyboranyl)-5-nitrobenzoic acid | HCID 2773315 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-Amino-5-carboxybenzeneboronic acid | HCID 2737795 | — |
Reaction Steps
A solution of 3-nitro-5-carboxyphenylboronic acid (3.3 g, 0.016 mol) in absolute ethanol (25 ml) was hydrogenated in the presence of Raney Nickel (1 g) at 50 lbs per square inch for 4 hours in a Parr shaker. The catalyst was removed by filtration and the solvent was removed on a rotary evaporator. The solid obtained was recrystallized from water. M.P. 210°-12° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05183653 |
| Source dataset | uspto-grants-1993_02 |
| ORD ID | ord-a056b2747fc642c888a1c555e1156aee |
| Source note | uspto-grants-1993_02 |