Anisole → HCID 22420677, compound

Participants

Reaction Steps

α-Bromopropiophenone (1.52 ml) and 1 ml of anisole were added to 2.57 grams of 5,6-dichloro-1-isopropyl-2-methylbenzimidazole and, after heating for 2 hours on a steam bath, 50 ml of acetone was added. The crystals which were produced were recovered by filtration, 40 ml of a 2% aqueous sodium carbonate solution was added and the mixture was heated for 80 minutes on a steam bath. After cooling, the crystals which had been formed were recovered by crystallization, washed with water and 6,7-dichloro-4-isopropyl-1-methyl-2-phenylpyrrolo(1,2-a)benzimidazole was obtained.

Provenance & Evidence