HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromomethylnaphthalene → HCID 19799303, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromomethylnaphthalene | HCID 70320 | — |
| Reactant | Ethyl 3-oxohexanoate | HCID 238498 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Solvent | Tetrahydrofuran ethanol | HCID 21873804 | — |
| Product | HCID 19799303 | HCID 19799303 | — |
Reaction Steps
Ethyl-α-(2-naphthalenylmethyl)-butyrylacetate was prepared following the procedure of Example 2 from 2.18 g of sodium, 15 g of ethyl butyrylacetate and 21 g of 2-naphthalenylmethyl bromide in 300 mL ethanol-THF (10:1). The crude product was purified by removal of excess starting β-keto ester using a kugelrohr apparatus (oven ≤100° C./0.50 mm).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05183825 |
| Source dataset | uspto-grants-1993_02 |
| ORD ID | ord-262a205ba0e545c39cbf3e2eb14f25e9 |
| Source note | uspto-grants-1993_02 |