N-bromobutanimide → 5-(Bromomethyl)benzo[b]thiophene

HRID 2081179Notes

Reaction equation

[CH3:1][C:2]1[CH:10]=[CH:9][C:5]2[S:6][CH:7]=[CH:8][C:4]=2[CH:3]=1.[Br:11]N1C(=O)CCC1=O>>[Br:11][CH2:1][C:2]1[CH:10]=[CH:9][C:5]2[S:6][CH:7]=[CH:8][C:4]=2[CH:3]=1

Participants

Reactant 2

HCID 67184N-bromobutanimide

HCID 843465-Methylbenzo(b)thiophene

Product 1

HCID 111604985-(Bromomethyl)benzo[b]thiophene

Procedure

5-Bromomethylbenzo[b]thiophene was prepared from 5-methylbenzo[b]thiophene and N-bromosuccinimide as in Example 6 except that the reaction was refluxed 15 hours.

Workup

temperaturewas refluxed 15 hours

Sources & evidence

ORD record: ord-3630df4e090a49c98c76ab3122f1ee54
Source dataset: uspto-grants-1993_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05183825

Reaction notes

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