Aniline → HCID 19799476, compound

Participants

Reaction Steps

A mixture of 3-cyano-2-benzoyl-1-hydroxy-indole (2.62 g, 10.0 mmole) and aniline (1.0 g, 10.8 mmole) were heated at reflux in toluene (50 ml) under a trap for 16 hours. Concentration in vacuo afforded a solid. Recrystallization from methylcyclohexane provided dark crystals, m.p. 188°-190° C. Analysis (dry 25° C.): Fd(calculated) N, 12.2 (12.4), C, 78.2 (78.3) H, 4.7 (4.5).

Provenance & Evidence