HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Undecyn-3-ol, 1-(trimethylsilyl)- → 1-Undecyn-3-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Undecyn-3-ol, 1-(trimethylsilyl)- | HCID 10890043 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | 1-Undecyn-3-ol | HCID 247766 | 92.3% |
Reaction Steps
10 g of (3RS)-1-(trimethylsilyl)-1-undecin-3-ol is dissolved in a mixture of 420 ml of 0.1 n sodium hydroxide solution and 420 ml of methanol and stirred for 3 hours at room temperature. Then, the methanol is removed in a vacuum, shaken with diethyl ether, dried (Na2SO4) and concentrated by evaporation. 6.46 g of (3RS)-1-undecin-3-ol is obtained as a yellow oil, which is further reacted as a crude product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05183925 |
| Source dataset | uspto-grants-1993_02 |
| ORD ID | ord-2eb0498c37054905bbf74437d84afe6c |
| Source note | uspto-grants-1993_02 |