反应详情

Under the conditions of example 2D, 612 mg of 2-(2-iodophenoxy)-ethyl acetate and 3.2 g of (E)-1,2-bis-(tri-n-butylstannyl)-ethylene (50%) is reacted in the presence of 47 mg of tetrakis-(triphenylphosphine)-palladium, treated with 1.02 g of iodine, worked up and chromatographed on silica gel with n-hexane/ethyl acetate=95/5. 280 mg of 2-[2-[(E)-2-iodovinyl]-phenoxy]-ethyl acetate is obtained as an oily crude product, which is used without further purification in the next stage.

1. customchromatographed on silica gel with n-hexane/ethyl acetate=95/5