Methyl Isocyanate → 3-[3-(Aminocarbonyl)phenoxy]-N-methyl-1-azetidinecarboxamide
Reaction equation
[NH:1]1[CH2:4][CH:3]([O:5][C:6]2[CH:7]=[C:8]([CH:12]=[CH:13][CH:14]=2)[C:9]([NH2:11])=[O:10])[CH2:2]1.[CH3:15][N:16]=[C:17]=[O:18]>>[CH3:15][NH:16][C:17]([N:1]1[CH2:4][CH:3]([O:5][C:6]2[CH:14]=[CH:13][CH:12]=[C:8]([C:9]([NH2:11])=[O:10])[CH:7]=2)[CH2:2]1)=[O:18]Participants
3
Procedure
The compound was prepared from 3-(3-azetidinyloxy) benzamide and methylisocyanate as described in Example 6 of U.S. Pat. No. 4,226,861, m.p. 238°-240° C.
Sources & evidence
- ORD record
- ord-98d845202d26433587b76c4db7dbbb27
- Source dataset
- uspto-grants-1993_02
- Patent number
- US05183902
Reaction notes
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