HCID 131716656, compound → HCID 131716654, compound

HRID 2081496Notes

Reaction equation

HRID 2081496 reaction equation
[P:1]([O-:42])([O:32][CH:33]=[C:34]1[CH2:39][CH2:38][CH2:37][CH2:36][N+:35]1([CH3:41])[CH3:40])([O:3][CH2:4][CH:5]([O:24]CC1C=CC=CC=1)[CH2:6][O:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])=[O:2]>[Pd].C(O)C>[P:1]([O-:42])([O:32][CH:33]=[C:34]1[CH2:39][CH2:38][CH2:37][CH2:36][N+:35]1([CH3:41])[CH3:40])([O:3][CH2:4][CH:5]([OH:24])[CH2:6][O:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])=[O:2]

Participants

4

Reactant 1

HCID 131716656HCID 131716656, compound

Product 1

HCID 131716654HCID 131716654, compoundYield 86.1%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

The procedures of Example 8-(1) were repeated using 300 mg of 2-benzyloxy-3-hexadecyloxypropyl 1,1-dimethylpiperidinio-2-ylmethyl phosphate prepared in Example 9, 50 mg of palladium(5%)-carbon and 30 ml of ethanol, to give 220 mg of 3-hexadecyloxy-2-hydroxypropyl 1,1-dimethylpiperidinio-2-ylmethyl phosphate.

Sources & evidence

ORD record
ord-1e3ba722c07c47aa8089fcc6427860a5
Source dataset
uspto-grants-1993_02
Patent number
US05183811

Reaction notes

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