HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 19799131, compound → HCID 67858434, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 19799131 | HCID 19799131 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Product | HCID 67858434 | HCID 67858434 | — |
Reaction Steps
1-(1-Fluorophenyl)-3-isoquinolinecarboxylic acid was converted into its ethylester and then reduced using lithium aluminum hydride to obtain 1-(1-fluorophenyl)-3-isoquinolinemethanol. 1.26 g of the obtained 1-(1-fluorophenyl)-3-isoquinolinemethanol was reacted with 930 mg of methyl p-toluenesulfonate in the same manner as in Reference Example 10 to give 1.6 g of the desired compound as a pale orange-colored solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05183811 |
| Source dataset | uspto-grants-1993_02 |
| ORD ID | ord-47c0c8f901b349f5871fa268116549e3 |
| Source note | uspto-grants-1993_02 |