Hydrogen Bromide → HCID 19779915, compound

Participants

Reaction Steps

2 g (0.006 mol) of 5-trifluoromethyl-4-chloro-3-(3'-ethoxy-4-chlorophenoxy)-1-methylpyrazole was combined with 2 ml of HBr and 0.16 g of methyl tricapryl ammonium chloride and refluxed with stirring for 20 hours after removing aqueous forerun. The mixture was poured into water and extracted with ether. The ether layer was washed with water and brine, stirred with MgSO4, filtered and evaporated to a solid which was purified by chromatography to give 0.9 g of a white solid m.p. 106°-108° C.

Provenance & Evidence