Hydrogen Peroxide → HCID 19780249, compound

Participants

Reaction Steps

A solution of 2-p-chlorobenzylpyridine (12.0 g, 0.059 moles) and hydrogen peroxide (33% w/v, 4.02 g, 12.2 ml, 0.118 moles) in glacial acetic acid (40 ml) was heated at 60° for 15 hours. The reaction mixture was cooled to room temperature, the acetic acid evaporated under reduced pressure and the residue dissolved in chloroform. After neutralisation with potassium carbonate (20 g) the chloroform was removed to give 2-p-chlorobenzylpyridine-N-oxide (11.02 g, 85%) as a viscous oil.

Provenance & Evidence