HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopentanone → 1-(2,5-Dihydro-1H-pyrrol-1-yl)cyclopentanecarbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopentanone | HCID 8452 | — |
| Reactant | Potassium Cyanide | HCID 9032 | — |
| Reactant | 3-Pyrroline | HCID 66059 | — |
| Reactant | 1-(Dimethylamino)cyclopentanecarbonitrile | HCID 10773049 | — |
| Solvent | Water | HCID 962 | — |
| Product | 1-(2,5-Dihydro-1H-pyrrol-1-yl)cyclopentanecarbonitrile | HCID 59347862 | 64% |
Reaction Steps
The title compound (2.8 g; 64%) was prepared from 3-pyrroline (1.86 g; 27 mmol), cyclopentanone (2.26 g; 27 mmol) and potassium cyanide (1.75 g; 27 mmol) in water (15 ml) in a similar manner to that described in D1. 1H NMR (CDCl3) δ: 1.85 (6H, m), 2.08 (2H, m), 3.61 (4H, s), 5.78 (2H, s).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07745642B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-472fc72622194db09a92f365d981acb1 |
| Source note | uspto-grants-2010_06 |