2,6-Diisopropylphenyl isocyanate → HCID 19780333, compound

Participants

Reaction Conditions

Reaction Steps

A slurry of 1-acetyl-5-amino-3-undecyl-1,2,4-triazole (3.56 g, 12.7 mmol) was warmed until homogeneous. 2,6-Diisopropylphenyl isocyanate (2.71 mL, 12.7 mmol) was added and the resulting solution was heated under reflux for 15 hours. The resulting solution was cooled (20° C.) and the precipitate was removed by filtration. The filtrate was concentrated in vacuo and the resulting oil was chromatographed on silica (85:15 hexane:ethyl acetate) to yield 4.07 g (66.3%) of the title compound as a light yellow oil.

Provenance & Evidence