Benzylamine → HCID 14749919, compound

HRID 2081669Notes

Reaction equation

HRID 2081669 reaction equation
[OH:1][CH2:2][C:3]1O[CH:5]=[C:6]([O:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[C:7](=[O:9])[CH:8]=1.[CH2:29]([NH2:36])[C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1>O>[CH2:29]([N:36]1[CH:5]=[C:6]([O:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[C:7](=[O:9])[CH:8]=[C:3]1[CH2:2][OH:1])[C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1

Participants

4

Reactant 2

HCID 7504BenzylamineHCID 14749912HCID 14749912, compound

Product 1

HCID 14749919HCID 14749919, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
50 °C

Procedure

A mixture of 50.0 g (0.127 mole) 2-hydroxymethyl-5-octadecyloxy-4-pyranone and 70 mL benzylamine is stirred for 2 hours at 100°-110° C. After cooling to about 50° C., the dark solution is mixed with 400 mL water and stirred. The precipitate thus formed is filtered off, washed, dried and recrystallized from propan-2-ol with thee addition of active charcoal, colorless crystals thereby being obtained; m.p. 120°-121° C.

Workup

  1. stirringstirred
  2. customThe precipitate thus formed
  3. filtrationis filtered off
  4. washwashed
  5. customdried
  6. customrecrystallized from propan-2-ol with thee addition of active charcoal, colorless crystals
  7. customthereby being obtained

Sources & evidence

ORD record
ord-743b01ce6395492bbb15e7850b74f4f8
Source dataset
uspto-grants-1993_02
Patent number
US05185352

Reaction notes

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