Acetic Anhydride → HCID 19780357, compound

Participants

Reaction Steps

5,10-Dihydro-2-(N-Ethylamino)indeno[1,2-b]indole (0.47 g, 1,90 mM) and acetic anhydride (4 cm3) were heated to 90°-95° C. for 4 hours. Water (30 cm3) was added to the cold solution and the mixture was stirred vigorously for 1 hour. The solid product which formed was then collected and washed with a few drops of cold ethanol to afford the title compound 0.5 g, 90% as a colourless solid, M.p. 232° C. 1H NMR (CDCl3) δ: 1.16 (3H, t, J=7.0 Hz), 1.90 (3H, s), 3.73 (2H, s), 3.81 (2H, q, J=7.0 Hz), 7.05-7.20 (4H, m), 7.46 (1H, d, J=7.5 Hz), 7.57 (1H, d, J=8.0 Hz), 7.63 (1H, d, J=7.0 Hz, 10.36 (1H, s)).

Provenance & Evidence