HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 19780396, compound → HCID 19780392, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 19780396 | HCID 19780396 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | HCID 19780392 | HCID 19780392 | — |
Reaction Steps
A suspension of the methyl ester (Example 32) (5.72 g) in 2N sodium hydroxide (35 ml) and methanol (140 ml) was heated under reflux for 6 hours. The reaction mixture was cooled and concentrated in vacuo. Acidification with aqueous hydrochloric acid and filtration gave 1-(3-nitrobenzyl)indoline-5-carboxylic acid, m.p. 259°-262° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05185361 |
| Source dataset | uspto-grants-1993_02 |
| ORD ID | ord-4e75637df9b545ee88da9e548c04a17e |
| Source note | uspto-grants-1993_02 |