Methyl Isocyanate → HCID 19780478, compound

HRID 2081754Notes

Reaction equation

[Br:1][C:2]1[S:6][C:5]([CH2:7][NH:8][OH:9])=[CH:4][CH:3]=1.[CH3:10][N:11]=[C:12]=[O:13]>>[OH:9][N:8]([CH2:7][C:5]1[S:6][C:2]([Br:1])=[CH:3][CH:4]=1)[C:12]([NH:11][CH3:10])=[O:13]

Participants

Reactant 2

HCID 12228Methyl Isocyanate

HCID 19780448HCID 19780448, compound

Product 1

HCID 19780478HCID 19780478, compound

Procedure

The title compound is prepared from (5-bromothien-2-yl)methyl hydroxylamine from Example 127 by reaction with methyl isocyanate instead of trimethylsilylisocyanate.

Sources & evidence

ORD record: ord-ac12ad9d71a744beab6143d9a5ffd0e4
Source dataset: uspto-grants-1993_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05185363

Reaction notes

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