HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-[2-Butyl-3-(2-chloro-benzyl)-3H-imidazol-4-yl]-2-thiophen-2-ylmethyl-acrylic acid → (E)-3-[2-n-Butyl-1-{4-carboxyphenyl}-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-[2-Butyl-3-(2-chloro-benzyl)-3H-imidazol-4-yl]-2-thiophen-2-ylmethyl-acrylic acid | HCID 10047444 | — |
| Reactant | 2-n-Butyl-1-(4-carboethoxy-2-chlorobenzyl)imidazole-5-aldehyde | HCID 19936789 | — |
| Reactant | (4-Carboethoxyphenyl]imidazole-5-aldehyde | HCID 86746550 | — |
| Product | (E)-3-[2-n-Butyl-1-{4-carboxyphenyl}-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic acid | HCID 14952944 | — |
Reaction Steps
The title compound was prepared following the procedure of Example 42 replacing 2-n-butyl-1-[(4-carboethoxy-2-chlorophenyl)methy]imidazole-5-aldehyde with 2-n-butyl-[(4-carboethoxyphenyl]imidazole-5-aldehyde; mp 260°-265° C.(d).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05185351 |
| Source dataset | uspto-grants-1993_02 |
| ORD ID | ord-4cd1c1ee96d04557bae5c28f71026316 |
| Source note | uspto-grants-1993_02 |