Butylamine → HCID 3738431, compound

HRID 2081891Notes

Reaction equation

HRID 2081891 reaction equation
[N+:1]([C:4]1[CH:9]=[C:8]([CH3:10])[CH:7]=[C:6]([N+:11]([O-:13])=[O:12])[C:5]=1Cl)([O-:3])=[O:2].[CH2:15]([NH2:19])[CH2:16][CH2:17][CH3:18]>O>[N+:1]([C:4]1[CH:9]=[C:8]([CH3:10])[CH:7]=[C:6]([N+:11]([O-:13])=[O:12])[C:5]=1[NH:19][CH2:15][CH2:16][CH2:17][CH3:18])([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 8007ButylamineHCID 789184-Chloro-3,5-dinitrotoluene

Product 1

HCID 3738431HCID 3738431, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

0.05 mol (10.8 g) of 2,6-dinitro-4-methylchlorobenzene is added gradually, in the course of 10 minutes, whilst stirring, to 25 ml of butylamine, the reaction medium being cooled as necessary so as not to exceed 50° C. When the addition has ended, stirring is maintained for 5 minutes and the reaction medium is then poured into 100 ml of iced water. The expected product precipitates and is filtered off, washed with water and recrystallised from ethanol. After drying in vacuo, it melts at 52° C.

Workup

  1. temperaturethe reaction medium being cooled as necessary so as not
  2. customto exceed 50° C
  3. additionWhen the addition
  4. temperatureis maintained for 5 minutes
  5. customThe expected product precipitates
  6. filtrationis filtered off
  7. washwashed with water
  8. customrecrystallised from ethanol
  9. customAfter drying in vacuo, it melts at 52° C.

Sources & evidence

ORD record
ord-4f2788c683df47f6aa9acce84d9f464e
Source dataset
uspto-grants-1993_02
Patent number
US05186717

Reaction notes

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