Ethanolamine → HCID 13000861, compound

HRID 2081893Notes

Reaction equation

HRID 2081893 reaction equation
[N+:1]([C:4]1[CH:9]=[C:8]([CH3:10])[CH:7]=[C:6]([N+:11]([O-:13])=[O:12])[C:5]=1Cl)([O-:3])=[O:2].[CH2:15]([CH2:17][NH2:18])[OH:16]>O>[N+:1]([C:4]1[CH:9]=[C:8]([CH3:10])[CH:7]=[C:6]([N+:11]([O-:13])=[O:12])[C:5]=1[NH:18][CH2:17][CH2:15][OH:16])([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 700EthanolamineHCID 789184-Chloro-3,5-dinitrotoluene

Product 1

HCID 13000861HCID 13000861, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

0.35 mol (76 g) of 2,6-dinitro-4-methylchlorobenzene is added gradually, in the course of 10 minutes, whilst stirring, to 150 ml of ethanolamine, the reaction medium being cooled as necessary so as not to exceed 75° C. When the addition has ended, the stirring is maintained for 5 minutes and the reaction medium is then poured into 600 g of iced water. The expected product precipitates. It is filtered off, washed with water and then recrystallised from ethanol. After drying in vacuo, it melts at 131° C.

Workup

  1. temperaturethe reaction medium being cooled as necessary so as not
  2. customto exceed 75° C
  3. additionWhen the addition
  4. temperaturethe stirring is maintained for 5 minutes
  5. customThe expected product precipitates
  6. filtrationIt is filtered off
  7. washwashed with water
  8. customrecrystallised from ethanol
  9. customAfter drying in vacuo, it melts at 131° C.

Sources & evidence

ORD record
ord-4a42880591d54cddabeea270346d8b40
Source dataset
uspto-grants-1993_02
Patent number
US05186717

Reaction notes

Loading…