Bromide ion → Tert-butyl (1-(4-(2-bromoacetyl)phenyl)cyclobutyl)carbamate

HRID 208195Notes

Reaction equation

HRID 208195 reaction equation
[Br-:22].[Br-:23].[Br-:24].[C:1]([CH3:2])(=[O:3])[c:4]1[cH:5][cH:6][c:7]([C:10]2([NH:14][C:15]([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:21])[CH2:11][CH2:12][CH2:13]2)[cH:8][cH:9]1.[CH2:25]([N+:26]([CH2:27][CH2:28][CH2:29][CH3:30])([CH2:31][CH2:32][CH2:33][CH3:34])[CH2:35][CH2:36][CH2:37][CH3:38])[CH2:39][CH2:40][CH3:41].[CH2:42]([N+:43]([CH2:44][CH2:45][CH2:46][CH3:47])([CH2:48][CH2:49][CH2:50][CH3:51])[CH2:52][CH2:53][CH2:54][CH3:55])[CH2:56][CH2:57][CH3:58].[CH2:59]([N+:60]([CH2:61][CH2:62][CH2:63][CH3:64])([CH2:65][CH2:66][CH2:67][CH3:68])[CH2:69][CH2:70][CH2:71][CH3:72])[CH2:73][CH2:74][CH3:75].[CH3:80][OH:81].[CH:76]([Cl:77])([Cl:78])[Cl:79].[Cl:82][CH2:83][Cl:84]>>[C:1]([CH2:2][Br:22])(=[O:3])[c:4]1[cH:5][cH:6][c:7]([C:10]2([NH:14][C:15]([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:21])[CH2:11][CH2:12][CH2:13]2)[cH:8][cH:9]1

Participants

7

Reactant 6

HCID 259Bromide ion3×HCID 887MethanolHCID 6212ChloroformHCID 6344DichloromethaneHCID 16028Tetrabutylammonium3×HCID 69087654HCID 69087654, compound

Product 1

HCID 86664668Tert-butyl (1-(4-(2-bromoacetyl)phenyl)cyclobutyl)carbamate

Sources & evidence

ORD record
ord-ced8fc2bda574a3d8b45b382152b4fba
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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