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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2081967Generated: October 25, 2026

Boc-Leu-Ala-OBzl → H-Leu-Ala-OBzl

https://huagongshe.com/reaction/2081967

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBoc-Leu-Ala-OBzlHCID 58901353—
SolventTrifluoroacetic acidHCID 6422—
ProductH-Leu-Ala-OBzlHCID 16742166—
ProductBoc-Leu-Ala-OBzlHCID 58901353—

Reaction Steps

Boc-Leu-Ala-OBzl was prepared by the procedure for dipeptide synthesis in Example 2. Boc-Leu-Ala-OBzl (23.7 g, 57.7 mmoles) was dissolved in 40 mL of anhydrous trifluoroacetic acid. After 15 min, excess trifluoroacetic acid was removed by evaporation and the residue was treated with ether to yield H-Leu-Ala-OBzl.trifluoroacetic acid as a crystalline product (22.8 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05187157
Source datasetuspto-grants-1993_02
ORD IDord-1f363856415640ab8c981b91f505f462
Source noteuspto-grants-1993_02