Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 208197Generated: October 25, 2026

1,4-Dioxa-8-azaspiro(4.5)decane → 8-(2,5-Difluoro-4-methoxyphenyl)-1,4-dioxa-8-azaspiro[4,5]decane

https://huagongshe.com/reaction/208197

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-Dioxa-8-azaspiro(4.5)decaneHCID 67435—
Reactant1-PhenethylpiperazineHCID 79214—
Reactant4-Bromo-1-methoxy-2-methylbenzeneHCID 608315—
Reactant4-Bromo-2,5-difluoroanisoleHCID 2724983—
Product8-(2,5-Difluoro-4-methoxyphenyl)-1,4-dioxa-8-azaspiro[4,5]decaneHCID 23111420—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-045859fd5e5a4ecd950316d1164d56e1
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)