HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → L-Tryptophan ethyl ester hydrochloride (1:1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | L-Tryptophan | HCID 6305 | — |
| Product | L-Tryptophan ethyl ester hydrochloride (1:1) | HCID 134519 | — |
Reaction Steps
A mixture of L-tryptophan (14.3 g, 0.07 mol) in 200 ml of ethanol containing ~7 g of anhydrous HCl was refluxed for 5 hours. The mixture was cooled and the solid which separated was recrystallized from ethanol/ether. Yield 17.4 g (92.5%), m.p. 226°-228° C. The product has the formula: ##STR1587## The product may also be named ethyl L-2-amino-3-indolepropionate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05187158 |
| Source dataset | uspto-grants-1993_02 |
| ORD ID | ord-86d16707902f4cd3bce67f3cc394296e |
| Source note | uspto-grants-1993_02 |