Benzoyl chloride → 3-(Benzoyloxy)-4-methyl-1,3-thiazole-2(3H)-thione

Participants

Reaction Steps

0.735 parts of 3-hydroxy-4-methylthiazol-2(3H)-thione were stirred in 50 parts of water and 0.84 parts of sodium hydrogen carbonate. The solution was screened and 0.9 parts of benzoyl chloride were added. The reaction mixture was stirred overnight at room temperature. A precipitate was formed which was separated by filtration, washed with cold water and recrystallised from ethanol to give 3-benzoyloxy-4-methylthiazol-2(3H)-thione, m.pt. 100°-102° C. By analysis the composition was found to be C, 52.4% wt; H, 3.6% wt; N, 5.6% wt and S, 25% wt. C11H9NO2S2 requires C, 52.6% wt; H, 3.6% wt; N, 5.6% wt and S, 25.5% wt.

Provenance & Evidence