Azido(trimethyl)stannane → HCID 178441896, compound

HRID 2082061Notes

Reaction equation

HRID 2082061 reaction equation
[CH2:1]([C:5]1[N:6]([CH2:15][C:16]2[CH:21]=[CH:20][C:19]([C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=3[C:28]#[N:29])=[CH:18][CH:17]=2)[C:7]2[N:8]([CH:10]=[C:11]([CH2:13][CH3:14])[N:12]=2)[N:9]=1)[CH2:2][CH2:3][CH3:4].C[Sn]([N:34]=[N+:35]=[N-:36])(C)C>>[CH2:1]([C:5]1[N:6]([CH2:15][C:16]2[CH:17]=[CH:18][C:19]([C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=3[C:28]3[NH:36][N:35]=[N:34][N:29]=3)=[CH:20][CH:21]=2)[C:7]2[N:8]([CH:10]=[C:11]([CH2:13][CH3:14])[N:12]=2)[N:9]=1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 5104973Azido(trimethyl)stannaneHCID 10430051HCID 10430051, compound

Product 1

HCID 178441896HCID 178441896, compoundYield 24%

Procedure

Reaction of 2-butyl-3-[(2'-cyanobiphenyl-4-yl)methyl]-5-ethyl-3H-imidazo[1,2-b][1,2,4]triazole (from Steps B and C) with trimethyltin azide according to the procedure of Example 1, Step G, gave a 24% yield of the title compound as a light tan solid, mp>100° C. (gradual); homogeneous by TLC in 90:10:0.1 CH2Cl2 -MeOH-AcOH.

Sources & evidence

ORD record
ord-fb36a007707249a98fa1665b4091885b
Source dataset
uspto-grants-1993_02
Patent number
US05187179

Reaction notes

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