Formic Acid → HCID 19779521, compound

HRID 2082075Notes

Reaction equation

HRID 2082075 reaction equation
[CH2:1]([N:3]([CH2:19][CH3:20])[CH2:4][CH2:5][CH2:6][S:7]([C:10]1[CH:15]=[CH:14][C:13]([N+:16]([O-:18])=[O:17])=[CH:12][CH:11]=1)(=[NH:9])=[O:8])[CH3:2].C=O.[CH:23](O)=O.[OH-].[Na+]>O>[CH3:23][N:9]=[S:7]([CH2:6][CH2:5][CH2:4][N:3]([CH2:1][CH3:2])[CH2:19][CH3:20])([C:10]1[CH:15]=[CH:14][C:13]([N+:16]([O-:18])=[O:17])=[CH:12][CH:11]=1)=[O:8]

Participants

6

Reactant 4

HCID 284Formic AcidHCID 712FormaldehydeHCID 14798Sodium HydroxideHCID 9904386HCID 9904386, compound

Product 1

HCID 19779521HCID 19779521, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of S-(3-diethylaminopropyl)-S-(4-nitrophenyl)sulfoximine (0.03 mole), 17 ml of 37% formaldehyde, and 22.6 ml of 98% formic acid is heated at reflux temperature for 48 hr. Water is added to the reaction mixture which is then made slightly basic by addition of 50% sodium hydroxide solution. The mixture is extracted with chloroform and the extract is dried and concentrated to obtain the title compound.

Workup

  1. temperatureis heated
  2. temperatureat reflux temperature for 48 hr
  3. extractionThe mixture is extracted with chloroform
  4. customthe extract is dried
  5. concentrationconcentrated

Sources & evidence

ORD record
ord-e0dd6210bb8b435288673053e075e06c
Source dataset
uspto-grants-1993_02
Patent number
US05187189

Reaction notes

Loading…