HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → HCID 21801030, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | 3,4-dihydro-2H-pyran | HCID 8080 | — |
| Reactant | Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1) | HCID 466102 | — |
| Reactant | t-Butoxycarbonylaminoethanol | HCID 22620026 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 21801030 | HCID 21801030 | — |
Reaction Steps
A solution of N-t-butoxycarbonylaminoethanol (2.0 g), dihydropyran (1.7 ml) and pyridinium p-toluenesulphonate (310 mg) in anhydrous dichloromethane (90 ml) was stirred at room temperature for 2 1/2 hours. Ether (150 ml) was added, the solution was washed with water (2×50 ml), dried, and the solvent removed under reduced pressure to give 2-(2-(2-(N-t-butoxycarbonylamino)ethoxy)tetrahydropyran (3.0 g) as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05187190 |
| Source dataset | uspto-grants-1993_02 |
| ORD ID | ord-13e16010fb564dee9ae3d964eb25810f |
| Source note | uspto-grants-1993_02 |