4,5-Dichlorophthalic anhydride → HCID 13365966, compound

HRID 2082135Notes

Reaction equation

HRID 2082135 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[O:10])[O:8][C:6](=O)[C:5]2=[CH:11][C:12]=1[Cl:13].[NH2:14][CH2:15][CH2:16][CH2:17][CH2:18][N:19]1[CH2:24][CH2:23][N:22]([C:25]2[N:30]=[CH:29][C:28]([C:31]3[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=3)=[CH:27][N:26]=2)[CH2:21][CH2:20]1>N1C=CC=CC=1>[C:31]1([C:28]2[CH:29]=[N:30][C:25]([N:22]3[CH2:21][CH2:20][N:19]([CH2:18][CH2:17][CH2:16][CH2:15][N:14]4[C:6](=[O:8])[C:5]5[C:4](=[CH:3][C:2]([Cl:1])=[C:12]([Cl:13])[CH:11]=5)[C:9]4=[O:10])[CH2:24][CH2:23]3)=[N:26][CH:27]=2)[CH:32]=[CH:33][CH:34]=[CH:35][CH:36]=1

Participants

4

Reactant 2

HCID 703344,5-Dichlorophthalic anhydrideHCID 13366001HCID 13366001, compound

Product 1

HCID 13365966HCID 13365966, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

0.005 mol of 4,5-dichlorophthalic anhydride and 0.005 mol of 1-(4-aminobutyl)-4-(5-phenyl-2-pyrimidinyl)piperazine in 20 ml of absolute pyridine are boiled under reflux, under an atmosphere of N2, for several hours. After cooling, the product which has crystallised out is filtered off and washed with isopropyl ether.

Workup

  1. temperatureunder reflux, under an atmosphere of N2, for several hours
  2. temperatureAfter cooling
  3. customthe product which has crystallised out
  4. filtrationis filtered off
  5. washwashed with isopropyl ether

Sources & evidence

ORD record
ord-a0d499112f7b4cd6b6b748f4192523e4
Source dataset
uspto-grants-1993_02
Patent number
US05187276

Reaction notes

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