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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2082178Generated: October 31, 2026

2-Chloroethyl isocyanate → HCID 18612287, compound

https://huagongshe.com/reaction/2082178

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloroethyl isocyanateHCID 16035—
Reactant1-Propanol, 2-methoxy-3-(octadecyloxy)-, (2S)-HCID 459930—
Solvent1,1-DichloroethaneHCID 6365—
ProductHCID 18612287HCID 18612287—

Reaction Conditions

Temperature80 °C

Reaction Steps

A solution of 0.17 g of (S)-2-O-methyl-1-O-octadecylglycerine in 10 ml of dichloroethane is treated with 1 ml of 2-chloroethyl isocyanate and heated at 80° C. for 25 hours. The solution is evaporated and the residue is chromatographed on silica gel. After elution with dichloromethane-ether (9:1), there is obtained (R)-1-O-[(2-chloroethyl)carbamoyl]-2-O-methyl-3-O-octadecylglycerine in the form of an oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05187293
Source datasetuspto-grants-1993_02
ORD IDord-0c37e617dce44138aab735acfa15cc45
Source noteuspto-grants-1993_02