Phosphorus pentachloride → 4-Carbobenzoxyoxybenzoyl chloride

HRID 2082185Notes

Reaction equation

HRID 2082185 reaction equation
[C:1]([O:11][C:12]1[CH:20]=[CH:19][C:15]([C:16](O)=[O:17])=[CH:14][CH:13]=1)([O:3][CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=[O:2].P(Cl)(Cl)(Cl)(Cl)[Cl:22]>CCOCC>[C:1]([O:11][C:12]1[CH:20]=[CH:19][C:15]([C:16]([Cl:22])=[O:17])=[CH:14][CH:13]=1)([O:3][CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=[O:2]

Participants

4

Reactant 2

HCID 24819Phosphorus pentachlorideHCID 179141024-{[(Benzyloxy)carbonyl]oxy}benzoic acid

Product 1

HCID 197340544-Carbobenzoxyoxybenzoyl chlorideYield 57%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A solution of 27 m moles (7.3 g) of the above 4-carbobenzoxyoxybenzoic acid and 27 m moles (5.6 g) of phosphorus pentachloride in 50 ml of ether was stirred for 24 hours at room temperature. After the reaction, deetherizing was carried out, and the obtained crystal was recrystallized from hexane, to obta. 4.5 g of 4-carbobenzoxyoxybenzoyl chloride [m.p. 0.5.5°-67.4° C⟧ (yield: 57%)

Workup

  1. customAfter the reaction
  2. customthe obtained crystal was recrystallized from hexane, to obta
  3. custom5.5°-67.4° C

Sources & evidence

ORD record
ord-6173e8e1ada54d6491ca7f5c87e87989
Source dataset
uspto-grants-1993_02
Patent number
US05187298

Reaction notes

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