1-Ethynylcyclohexanol → HCID 15172931, compound

Participants

Reaction Steps

The procedure of Example 1 was repeated except that 1.14 g (2.9 mmol) of 2-iodoadenosine was used as the starting compound, that the cyclohexylacetylene was replaced by 1-ethynyl-1-cyclohexanol, and that the reaction was carried out at a temperature of 100° C. for one hour, respectively, whereby 0.91 g (2.3 mmol) of crystalline 2-[(1-hydroxycyclohexane-1-yl)ethynyl]adenosine was obtained (yield: 79%).

Provenance & Evidence