1-Carbobenzoxy-4-piperidinecarboxylic Acid → 4-Butoxycarbonylamino-piperidine-1-carboxylic acid benzyl ester

HRID 2082309Notes

Reaction equation

HRID 2082309 reaction equation
[C:1]1([CH2:7][O:8][C:9]([N:11]2[CH2:16][CH2:15][CH:14](C(O)=O)[CH2:13][CH2:12]2)=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>C(O)CCC>[CH2:7]([O:8][C:9]([NH:11][CH:14]1[CH2:13][CH2:12][N:11]([C:9]([O:8][CH2:7][C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)=[O:10])[CH2:16][CH2:15]1)=[O:10])[CH2:1][CH2:2][CH3:3]

Participants

3

Reactant 1

HCID 7364891-Carbobenzoxy-4-piperidinecarboxylic Acid

Product 1

HCID 668559504-Butoxycarbonylamino-piperidine-1-carboxylic acid benzyl ester

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

In a manner similar to that described in Preparation 6, 1-[(phenylmethoxy)carbonyl]piperidine-4-carboxylic acid and 1-butanol are reacted to give the title compound.

Workup

  1. customare reacted

Sources & evidence

ORD record
ord-f8b30e09d793409882124c938fc267d5
Source dataset
uspto-grants-1993_02
Patent number
US05189036

Reaction notes

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