Nicotinic Acid → HCID 19778065, compound

HRID 2082313Notes

Reaction equation

HRID 2082313 reaction equation
[C:1]([OH:9])(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[N:4][CH:3]=1.[N:10]1([C:15]2[CH:29]=[CH:28][C:18]([C:19]([N:21]3[CH2:26][CH2:25][CH:24]([NH2:27])[CH2:23][CH2:22]3)=[O:20])=[CH:17][CH:16]=2)[CH:14]=[CH:13][N:12]=[CH:11]1>>[N:10]1([C:15]2[CH:16]=[CH:17][C:18]([C:19]([N:21]3[CH2:26][CH2:25][CH:24]([NH:27][C:1]([C:2]4[CH:3]=[N:4][CH:5]=[CH:6][CH:7]=4)=[O:9])[CH2:23][CH2:22]3)=[O:20])=[CH:28][CH:29]=2)[CH:14]=[CH:13][N:12]=[CH:11]1

Participants

3

Reactant 2

HCID 938Nicotinic AcidHCID 19778044HCID 19778044, compound

Product 1

HCID 19778065HCID 19778065, compound

Procedure

In a manner similar to that described in Example 4, nicotinic acid and 1-[4-(1H-imidazol-1-yl)benzoyl]-4-piperidinamine are converted to the title compound.

Sources & evidence

ORD record
ord-34d609a779cf437989c0b816d668e3b6
Source dataset
uspto-grants-1993_02
Patent number
US05189036

Reaction notes

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