Tridecanoic acid → Tridecanoyl chloride

Participants

Reaction Steps

To a stirred solution of 13.2 grams (61.5 mmol) of tridecanoic acid in 80 mL of benzene was added 26.2 grams (206 mmol) of oxalyl chloride. After stirring for 20 minutes, the mixture was heated to reflux and maintained at reflux overnight. The mixture was cooled to room temperature and the solvent was removed at reduced pressure to provide 14.3 grams (100%) of tridecanoyl chloride as an orange oil which was used without any further purification.

Provenance & Evidence