HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aminoacetaldehyde dimethyl acetal → HCID 19778271, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aminoacetaldehyde dimethyl acetal | HCID 89728 | — |
| Reactant | 2-Isothiocyanatothiophene | HCID 12348170 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 19778271 | HCID 19778271 | — |
Reaction Steps
A mixture of 2-isothiocyanatothiophene (16.9 g, 0.12 mol) and aminoacetaldehyde dimethyl acetal (12.6 g, 0.12 mol) in 200 ml toluene is refluxed for 2 hours. After removal of the toluene, the residue is dissolved in 200 ml ethanol and 45 ml conc. HCl added. After the reaction is refluxed for 5 hours, it is poured onto ice. The product is collected and purified by recrystallization.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05189052 |
| Source dataset | uspto-grants-1993_02 |
| ORD ID | ord-1927766a5c0e46cfb1f4cb15bf4e9ddd |
| Source note | uspto-grants-1993_02 |