反应详情

100 mg of MnO2, prepared according to Attenburrow's method, are suspended in a carbon tetrachloride/methylene chloride (4:1) mixture containing 500 mg of alcohol (12). The reaction medium is stirred at room temperature for 11/2 hours. The oxidizing agent is then filtered on celite. 230 mg of compound (13) are obtained (Yld:46%). This compound is purified by chromatography on a silica column (eluent:ethyl acetate/hexane, 1:1). It has the appearance of a yellow oil.

1. filtrationThe oxidizing agent is then filtered on celite