HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl (methylsulfinyl)methyl sulfide → 2-(2,6-dichloro-4-trifluoromethylphenyl)-4-(2-methylthio-2-methylsulphinylvinyl)-2H-1,2,3-triazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl (methylsulfinyl)methyl sulfide | HCID 99129 | — |
| Reactant | 2-(2,6-Dichloro-4-trifluoromethylphenyl)-1,2,3-triazole-4-carboxaldehyde | HCID 19778308 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-(2,6-dichloro-4-trifluoromethylphenyl)-4-(2-methylthio-2-methylsulphinylvinyl)-2H-1,2,3-triazole | HCID 53829386 | — |
Reaction Steps
2-(2,6-Dichloro-4-trifluoromethylphenyl)-2H-1,2,3-triazole-4-carboxaldehyde (15 g) and methyl methylthiomethyl sulphoxide (6 ml) were heated under reflux in tetrahydrofuran (100 ml) containing Triton B solution (6 ml; 40% in methanol) for 12 hours. The mixture was worked up to give 2-(2,6-dichloro-4-trifluoromethylphenyl)-4-(2-methylthio-2-methylsulphinylvinyl)-2H-1,2,3-triazole, m.p. 122°-123°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05189053 |
| Source dataset | uspto-grants-1993_02 |
| ORD ID | ord-9a461b48ca1e43349cb66aafb76c009e |
| Source note | uspto-grants-1993_02 |