Formic Acid → HCID 178467450, 화합물

HRID 2082642노트

반응식

HRID 2082642 반응식
ClC1C=CN=NN=1.Cl[C:9]1[N:14]=[C:13]([O:15][CH2:16][CH3:17])[N:12]=[C:11]([N:18]([CH3:20])[CH3:19])[N:10]=1.C(O)=[O:22]>>[CH3:19][N:18]([CH3:20])[C:11]1[N:12]=[C:13]([O:15][CH2:16][CH3:17])[NH:14][C:9](=[O:22])[N:10]=1

참가 물질

4

반응물 3

HCID 284Formic AcidHCID 18318800Chloro-triazineHCID 233381422-Chloro-4-ethoxy-6-dimethylamino-1,3,5-triazine

생성물 1

HCID 178467450HCID 178467450, 화합물

실험 절차

The chlorotriazine from (b) (1.2 g.) was heated in formic acid (15 ml.) on a steam bath for 45 minutes, when gas evolution had ceased. The excess of formic acid was removed under reduced pressure and the residue was dissolved in the minimum amount of water, which was brought to pH 6-7 by adding solid sodium bicarbonate. The solution was extracted with chloroform and the extracts dried and evaporated. The residue crystallised from ethanol to give the product (1.1 g.) having a melting point of 215°-216° C. (The melting point sample resolidified and re-melted at 235° C).

후처리

  1. customThe excess of formic acid was removed under reduced pressure
  2. dissolutionthe residue was dissolved in the minimum amount of water, which
  3. additionby adding solid sodium bicarbonate
  4. extractionThe solution was extracted with chloroform
  5. customthe extracts dried
  6. customevaporated
  7. customThe residue crystallised from ethanol
  8. customto give the product (1.1 g.)

출처 및 근거

ORD 기록
ord-2a480e65c92c4208856ce8e33519673e
출처 데이터셋
uspto-grants-1978_04
특허 번호
US04082536

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