Cyclohexanone → HCID 12319054, compound

HRID 2082653Notes

Reaction equation

HRID 2082653 reaction equation
[C:1]1(=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:8]([NH:12][CH2:13][CH2:14][CH2:15][CH3:16])[CH2:9][CH2:10][CH3:11]>C1C=CC=CC=1>[C:1]1([N:12]([CH2:13][CH2:14][CH2:15][CH3:16])[CH2:8][CH2:9][CH2:10][CH3:11])[CH2:6][CH2:5][CH2:4][CH2:3][CH:2]=1

Participants

4

Reactant 2

HCID 7967CyclohexanoneHCID 8148Dibutylamine

Product 1

HCID 12319054HCID 12319054, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

This example shows a typical preparation of an enamine of this invention using a ketone. A half mole of both cyclohexanone and di-n-butylamine in 100 ml. of benzene were refluxed for 2-3 days using a Dean Stark trap to collect the water as it formed. After about 61/2 ml. of water was collected, the benzene was stripped off, and the enamine was collected as the fraction distilling between 121°-124° C. at 7.5 mm. Hg.

Workup

  1. customto collect the water as it
  2. customformed
  3. customof water was collected
  4. customthe enamine was collected as the fraction
  5. distillationdistilling between 121°-124° C. at 7.5 mm. Hg

Sources & evidence

ORD record
ord-08906821bb9c46b09ddbb5ae1324b01f
Source dataset
uspto-grants-1978_04
Patent number
US04082706

Reaction notes

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