HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → Ethyl (1E)-N-(2-benzoyl-4-chlorophenyl)ethanimidate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | 2-Amino-5-chlorobenzophenone | HCID 12870 | — |
| Reactant | Ethyl ortho-acetate | HCID 86598186 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | Ethyl (1E)-N-(2-benzoyl-4-chlorophenyl)ethanimidate | HCID 12463100 | — |
Reaction Steps
A solution of 11.5 parts of 2-amino-5-chlorobenzophenone, 11.5 parts of ethyl orthoacetate and 6 volume parts of acetic acid in 100 volume parts of benzene is refluxed for 20 minutes, whereby 5-chloro-2-(1-ethoxyethylideneamino)-benzophenone are obtained as crystals. Recrystallization from methanol-water gives colorless needles melting at 62° to 63° C. Yield: 93%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04082764 |
| Source dataset | uspto-grants-1978_04 |
| ORD ID | ord-9c8b00dbaf1a4b97b76b8291601a88d2 |
| Source note | uspto-grants-1978_04 |