HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 12535821, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Diethyl (ethoxymethylene)malonate | HCID 6871 | — |
| Reactant | Sodium ethoxide | HCID 2723922 | — |
| Reactant | HCID 20360312 | HCID 20360312 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 12535821 | HCID 12535821 | 76% |
Reaction Steps
Diethyl ethoxymethylenemalonate (1.18 g., 5.45 mmoles) was added to a cold, stirred mixture of sodium ethoxide (0.37 g., 5.45 mmoles) and 5-carbomethoxy-2-ethoxy-benzamidine (1.21 g., 5.45 mmoles) in ethanol (15 ml.). The mixture was poured onto ice-water and acidified with acetic acid. The precipitate was recrystallized from ethanol to give the title compound (1.49 g., 76%) as colorless crystals, m.p. 180°-181.5°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04082751 |
| Source dataset | uspto-grants-1978_04 |
| ORD ID | ord-59df0abd9f5f4fadb3d73c90e5f938ff |
| Source note | uspto-grants-1978_04 |