反应详情

A mixture of 2-(5-nitro-2-n-propoxyphenyl)-5-(5-1H-tetrazolyl)pyrimidine-4(3H)-one (5.0 g.) and 10% paladium-on-carbon (4.0 g.) in 2-methoxyethanol (900 ml.) was shaken in an atmosphere of hydrogen at an initial pressure of 3.5 kg./cm2 for 19 hours. The mixture was filtered and the filtrate evaporated to dryness to give the title compound (3.6 g., 79%), m.p. 250°-253° (decomp). Recrystallization from 2-methoxyethanol gave analytical material, m.p. 261°-262°.

1. filtrationThe mixture was filtered
2. customthe filtrate evaporated to dryness